Virtual slide formats understood by OpenSlide

OpenSlide’s support for these formats is not endorsed by their respective vendors and may be incomplete. Problems should be reported to the OpenSlide mailing list or issue tracker.

Aperio

Single-file pyramidal tiled TIFF, with non-standard metadata and compression.

File extensions
.svs, .tif
OpenSlide vendor backend
aperio
More info
Aperio format

DICOM

International standard multi-file medical imaging format.

File extensions
.dcm
OpenSlide vendor backend
dicom
More info
DICOM format

Hamamatsu

Multi-file JPEG/NGR with proprietary metadata and index file formats, and single-file TIFF-like format with proprietary metadata.

File extensions
.vms, .vmu, .ndpi
OpenSlide vendor backend
hamamatsu
More info
Hamamatsu format

Leica

Single-file pyramidal tiled BigTIFF with non-standard metadata.

File extensions
.scn
OpenSlide vendor backend
leica
More info
Leica format

MIRAX

Multi-file with very complicated proprietary metadata and indexes.

File extensions
.mrxs
OpenSlide vendor backend
mirax
More info
MIRAX format

Philips

Single-file pyramidal tiled TIFF or BigTIFF with non-standard metadata.

File extensions
.tiff
OpenSlide vendor backend
philips
More info
Philips format

Sakura

SQLite database containing pyramid tiles and metadata.

File extensions
.svslide
OpenSlide vendor backend
sakura
More info
Sakura format

Trestle

Single-file pyramidal tiled TIFF, with non-standard metadata and overlaps. Additional files contain more metadata and detailed overlap info.

File extensions
.tif
OpenSlide vendor backend
trestle
More info
Trestle format

Ventana

Single-file pyramidal tiled BigTIFF, with non-standard metadata and overlaps.

File extensions
.bif, .tif
OpenSlide vendor backend
ventana
More info
Ventana format

Generic tiled TIFF

Single-file pyramidal tiled TIFF.

File extensions
.tif
OpenSlide vendor backend
generic-tiff
More info
Generic tiled TIFF format